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OpenAI’s Fidji Simo takes medical depart, declares management adjustments

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Last updated: April 3, 2026 10:10 pm
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Published: April 3, 2026
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OpenAI’s Fidji Simo takes medical depart, declares management adjustments


Fidji Simo, chief govt officer of Instacart Inc., speaks throughout a Bloomberg Studio 1.0 interview in San Francisco, California, U.S., on Thursday, March 3, 2022.

David Paul Morris | Bloomberg | Getty Photos

Fidji Simo, OpenAI’s product and enterprise chief, introduced a number of management adjustments on Friday and revealed she is taking a major medical depart due to a worsening neuroimmune situation.

OpenAI employed Simo in Might, and she or he informed staffers in a memo on Friday that her situation, Postural Orthostatic Tachycardia Syndrome, or POTS, relapsed a couple of weeks earlier than she began within the function. She mentioned the previous month has been “significantly tough health-wise,” and she or he determined she must take a number of weeks off to recuperate.

“For my total time right here, I’ve postponed medical checks and new therapies to remain fully centered on the job and never miss a single day of labor,” Simo wrote within the memo, which was considered by CNBC. “I took day without work for the primary time two weeks earlier than the break for some medical checks, and it is now clear that I’ve pushed slightly too far and I really want to attempt new interventions to stabilize my well being.”

In an interview with CNBC in March, Simo mentioned she was recognized with POTS in 2019, and she or he noticed greater than 40 specialists as she tried to grasp her situation. Sufferers with POTS have problem preserving their blood strain regular, which may trigger signs like dizziness, fatigue and chest pains, based on the Cleveland Clinic. The situation may be difficult for health-care suppliers to diagnose.

Simo joined OpenAI after serving as CEO of Instacart, and she or he beforehand spent greater than a decade in a variety of management roles at Meta.

OpenAI President Greg Brockman will oversee product in Simo’s absence, she mentioned. Simo additionally introduced that Brad Lightcap, OpenAI’s chief working officer, will transition to a brand new function centered on “particular initiatives.” He’ll report on to OpenAI CEO Sam Altman.

Denise Dresser, the corporate’s chief income officer, will take over most of Lightcap’s tasks and report on to Simo. Dresser is not going to oversee Lightcap’s authorities or OpenAI for International locations work, which is now being folded underneath the corporate’s technique group.

Moreover, Simo introduced that Kate Rouch, OpenAI’s advertising chief, has determined to step right down to concentrate on her most cancers restoration. Rouch was recognized with late-stage breast most cancers roughly a yr and a half in the past, proper after she stepped into her function at OpenAI.

“I really like this job. I really like this staff. Which is precisely why I did not step away and did each — lead at OpenAI whereas going by means of intense most cancers therapy,” Rouch wrote in a publish on LinkedIn. “It is the toughest factor I’ve ever finished. At a sure level, it’s a must to be trustworthy about your limits. I’ve reached mine.”

Simo mentioned Rouch will return to a extra narrowly-scoped function when her well being permits, and OpenAI will lead a seek for her substitute.

“Now we have a powerful management staff centered on our largest priorities: advancing frontier analysis, rising our international person base of almost 1 billion customers, and powering enterprise use circumstances,” an OpenAI spokesperson mentioned in an announcement. “We’re well-positioned to maintain executing with continuity and momentum.”

WATCH: AI and Uncommon Illness with OpenAI CEO of Functions Fidji Simo

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